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Showing 1 to 12 of 199 entries
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The performance of MLEM for dynamic imaging from simulated few-view, multi-pinhole SPECT.

IEEE transactions on nuclear science

Ma D, Wolf P, Clough AV, Schmidt TG.
PMID: 24273334
IEEE Trans Nucl Sci. 2013 Feb;60(1). doi: 10.1109/TNS.2012.2214235.

Stationary small-animal SPECT systems are being developed for rapid dynamic imaging from limited angular views. This paper quantified, through simulations, the performance of Maximum Likelihood Expectation Maximization (MLEM) for reconstructing a time-activity curve (TAC) with uptake duration of a...

Performance Evaluation of Small Animal PET Scanners With Different System Designs.

IEEE transactions on nuclear science

Li X, Alessio AM, Burnett TH, Lewellen TK, Miyaoka R.
PMID: 24273335
IEEE Trans Nucl Sci. 2013 Jun;60(3). doi: 10.1109/TNS.2013.2246797.

This study evaluated the image quality metrics of small animal PET scanners based upon measured single detector module positioning performance. A semi-analytical approach was developed to study PET scanner performance in the scenario of multiple realizations. Positron range blurring,...

Impact of Analog IC Impairments in SiPM Interface Electronics.

IEEE transactions on nuclear science

Dey S, Lewellen TK, Miyaoka RS, Rudell JC.
PMID: 24817765
IEEE Trans Nucl Sci. 2012;2012:3572-3574. doi: 10.1109/NSSMIC.2012.6551818.

The recent realization of Silicon Photomultiplier (SiPM) devices as solid-state detectors for Positron Emission Tomography holds the promise of improving image resolution, integrating a significant portion of the interface electronics, and potentially lowering the power consumption. Our lab has...

First-Pass Angiography in Mice Using FDG-PET: A Simple Method of Deriving the Cardiovascular Transit Time Without the Need of Region-of-Interest Drawing.

IEEE transactions on nuclear science

Wu HM, Kreissl MC, Schelbert HR, Ladno W, Prins M, Shoghi-Jadid K, Chatziioannou A, Phelps ME, Huang SC.
PMID: 26478599
IEEE Trans Nucl Sci. 2005 Oct;52(5):1311-1315. doi: 10.1109/TNS.2005.858239.

In this study, we developed a simple and robust semi-automatic method to measure the right ventricle to left ventricle (RV-to-LV) transit time (TT) in mice using 2-[

TandemPET- A High Resolution, Small Animal, Virtual Pinhole-Based PET Scanner: Initial Design Study.

IEEE transactions on nuclear science

Raylman RR, Stolin AV, Martone PF, Smith MF.
PMID: 27041767
IEEE Trans Nucl Sci. 2016 Feb;63(1):75-83. doi: 10.1109/TNS.2015.2482459. Epub 2015 Oct 29.

Mice are the perhaps the most common species of rodents used in biomedical research, but many of the current generation of small animal PET scanners are non-optimal for imaging these small rodents due to their relatively low resolution. Consequently,...

Effect of Non-Alignment/Alignment of Attenuation Map Without/With Emission Motion Correction in Cardiac SPECT/CT.

IEEE transactions on nuclear science

Dey J, Segars WP, Pretorius PH, King MA.
PMID: 26543244
IEEE Trans Nucl Sci. 2015 Aug;62(4):1813-1824. doi: 10.1109/TNS.2015.2446895. Epub 2015 Jul 23.

PURPOSE: We investigate the differences without/with respiratory motion correction in apparent imaging agent localization induced in reconstructed emission images when the attenuation maps used for attenuation correction (from CT) are misaligned with the patient anatomy during emission imaging due...

Simulating Silicon Photomultiplier Response to Scintillation Light.

IEEE transactions on nuclear science

Jha AK, van Dam HT, Kupinski MA, Clarkson E.
PMID: 26236040
IEEE Trans Nucl Sci. 2013 Feb;30(1):336-351. doi: 10.1109/TNS.2012.2234135.

The response of a Silicon Photomultiplier (SiPM) to optical signals is affected by many factors including photon-detection efficiency, recovery time, gain, optical crosstalk, afterpulsing, dark count, and detector dead time. Many of these parameters vary with overvoltage and temperature....

Modeling the respiratory motion of solitary pulmonary nodules and determining the impact of respiratory motion on their detection in SPECT imaging.

IEEE transactions on nuclear science

Smyczynski MS, Gifford HC, Lehovich A, McNamara JE, Segars WP, Hoffman EA, Tsui BM, King MA.
PMID: 27182079
IEEE Trans Nucl Sci. 2016 Feb;63(1):117-129. doi: 10.1109/TNS.2015.2512840. Epub 2016 Feb 15.

The objectives of this investigation were to model the respiratory motion of solitary pulmonary nodules (SPN) and then use this model to determine the impact of respiratory motion on the localization and detection of small SPN in SPECT imaging...

Range Condition and ML-EM Checkerboard Artifacts.

IEEE transactions on nuclear science

You J, Wang J, Liang Z.
PMID: 18449363
IEEE Trans Nucl Sci. 2007 Oct;54(5):1696-1702. doi: 10.1109/TNS.2007.901198.

The expectation maximization (EM) algorithm for the maximum likelihood (ML) image reconstruction criterion generates severe checkerboard artifacts in the presence of noise. A classical remedy is to impose an a priori constraint for a penalized ML or maximum a...

Performance Characteristics of BGO Detectors for a Low Cost Preclinical PET Scanner.

IEEE transactions on nuclear science

Zhang H, Vu NT, Bao Q, Silverman RW, Berry-Pusey BN, Douraghy A, Williams DA, Rannou FR, Stout DB, Chatziioannou AF.
PMID: 21165154
IEEE Trans Nucl Sci. 2010 Jun 01;57(3):1038-1044. doi: 10.1109/TNS.2010.2046753.

PETbox is a low-cost benchtop PET scanner dedicated to high throughput preclinical imaging that is currently under development at our institute. This paper presents the design and characterization of the detectors that are used in the PETbox system. In...

Maximum-Likelihood Methods for Processing Signals From Gamma-Ray Detectors.

IEEE transactions on nuclear science

Barrett HH, Hunter WC, Miller BW, Moore SK, Chen Y, Furenlid LR.
PMID: 20107527
IEEE Trans Nucl Sci. 2009 Jun 01;56(3):725. doi: 10.1109/tns.2009.2015308.

In any gamma-ray detector, each event produces electrical signals on one or more circuit elements. From these signals, we may wish to determine the presence of an interaction; whether multiple interactions occurred; the spatial coordinates in two or three...

Monte Carlo Simulation Study on the Time Resolution of a PMT-Quadrant-Sharing LSO Detector Block for Time-of-Flight PET.

IEEE transactions on nuclear science

Liu S, Li H, Zhang Y, Ramirez RA, Baghaei H, An S, Wang C, Liu J, Wong WH.
PMID: 20559457
IEEE Trans Nucl Sci. 2009;56(5):2614-2620. doi: 10.1109/TNS.2009.2027903.

We developed a detailed Monte Carlo simulation method to study the time resolution of detectors for time-of-flight positron emission tomography (TOF PET). The process of gamma ray interaction in detectors, scintillation light emission and transport inside the detectors, the...

Showing 1 to 12 of 199 entries